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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

adj. 有营养的,滋养的
Keep around people who like to remind you how smart you are, and stay even though they think you are a dick.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Do you often feel gloomy and down in the dumps?
3. 《间谍之桥》(Bridge of Spies)。几年前,史蒂文·斯皮尔伯格(Steven Spielberg)进入了殿堂级导演的行列,从安德鲁·萨里斯(Andrew Sarris)所谓的“美国电影”中借鉴了最崇高的形式——这部影片中他仍然保持水准。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

对工业大宗商品需求的下降尤为明显。中国房地产和制造业的严重供应过剩在近几个月抑制了对新产能的投资,进而削弱了对各种原材料的需求。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

10月份,中国社会消费品零售总额增长放缓。另一方面,尽管上月出口走弱,中国规模以上工业增加值和全国固定资产投资增长仍大致保持平稳。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

5. "Dexter" (3.1 million)
productive
Actively expanding China's opening up to the world
“尽管我本质上是一名工程师和分析人员,但迄今为止我所做过的最重要的决定都与此无关,它们永远是基于直觉,”他去年在曾就读MBA的杜克大学(Duke University)对一名采访者表示。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

“Yao represents the new wave of wealth creation by financial investments in China,” said Rupert Hoogewerf, who compiles the annual list.
This is second major English-language role for the French actress, who co-stars opposite Daniel Craig in Skyfall as the enigmatic Severine. The movie opens Nov. 9 in North America but already is shattering records internationally.
Employers have stepped up their hiring recently, adding 171,000 jobs in October and an average of 157,000 a month so far this year. That's a better pace than last year and the strongest job growth since 2006, Labor Department data show.[qh]
The biggest story of the festival had nothing to do with films. It was about shoes. On Tuesday trade magazine Screen reported that a group of women had been denied access to a screening of Todd Haynes' Carol because their footwear – flat shoes with rhinestones – was unsuitable for the red carpet. Further tales came tumbling forth, social media erupted in indignation and soon enough we were soon dealing with a fully fledgedscandale. The Cannes press office rushed out a garbled statement: “Rules have not changed throughout the years (Tuxedo, formal dress for Gala screenings) and there is no specific mention about the height of the women's heels as well as for men's. Thus, in order to make sure that this rule is respected, the festival's hosts and hostesses were reminded of it.” Well, that cleared that up. Perhaps wisely, press screenings are exempt from any dress code: scruffy journalists are free to ascend the Palais' steps in flip flops and trainers.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

4、拖拉

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

No. Wall Street strategists’ predicting that the US government’s 10-year borrowing costs will climb above the 3 per cent mark in the coming year is as much a staple of the Christmas period as awkward office parties. This year the forecasts look more likely to be fulfilled, given a withdrawal of quantitative easing and the US tax cut. However, the seismic, secular forces pinning down both inflation and long-term bond yields remain in place and are still underestimated. The Federal Reserve will raise interest rates at least three times in 2018, but the 10-year yield will not breach 3 per cent.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

他们现在对阵克里夫兰和波士顿时的人员对位看起来顺眼多了。
5. bedazzled / a . 眼花缭乱的。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Romance was different then - with no computers, letter writing was the only way to stay in touch and remains more romantic than emails, he said.
国务院总理李克强在上周五由人力资源和社会保障部组织的一次会议上表示,要优先促进就业。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

The list also has some movies that earned awards at the 67th Berlin International Film Festival in February, such as the best movie winner On Body and Soul and best director winner The Other Side of Hope, by Aki Kaurismaki of Finland.
勤勉尽责干事创业。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 国外建材大佬中国水土不服
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Initial success was achieved in supply-side structural reform.
其中有铁环的那一个是在江苏西部的仪征市发现的。
12. 《教师》,导演:那达夫·拉皮德。
The Magic are the single-most mystifying team in this entire exercise. They make little sense on paper or on the court.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

The programme is ranked second for career progress three years after graduation. Tiemba’s graduates number only about 250 so far, making them an elite group.— LaurentOrtmans

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

源于:prim(adj 整洁的;最好的;早的)
“You can choose to spend the time however you like,” he wrote, suggesting people “go travelling, pursue a philanthropic project, spend quality time with family or simply take time out to recharge and refocus”.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Song “Unforgettable” (Li Guyi, Zhang Yingxi and students from Confucius Institute)

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Apple (AAPL, Fortune 500) announced that it would put $30 billion of its cash toward share repurchases. The news made investors happy: The stock popped, and even a week later was up 12% relative to the S&P over that same 7-day period. The buybacks were part of a larger $130 billion capital return program that the company said would extend through 2015.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

*最佳综艺导演:瑞安?麦克福(Ryan McFaul),《艾米?舒莫的内心世界》(Inside Amy Schumer)
《广告狂人》对时装的影响体现在品牌的发展当中,例如香蕉共和国(Banana Republic)就推出了《广告狂人》系列(这个系列是与该剧的服装主管贾妮·布赖恩特[Janie Bryant]联合设计的),而且很多心照不宣的地方在设计中更加随处可见:裁剪和印花,褶边和接缝;它的影响渗入了在秀台上普遍存在的一种鲜明理念:如果你缺乏灵感或者产生了审美怀疑,就去回顾60年代吧。
3. Portugal is entirely powered by renewable energy for four days
立场:呼吁结束政府停摆局面

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

2013年排名:2
自从2008年智能手机应用商店开始运营以来,达洛伊西奥就着手设计iPhone手机应用软件。那时12岁的他住在伦敦的温布尔顿,用卧室里的Mac电脑来工作。因为年纪太小,他在填写苹果(Apple)开发执照申请时用的都是他爸爸的名字。这之前他没在学校受过正式的电脑培训,他的父母(一个是律师,一个是商界管理人士)也都不从事技术行业工作。他几乎是完全靠刷网页、看教程来自学编程的。
[sin'si?li]
The ranking of 95 schools, up from 90 last year, includes nine institutions, from seven countries, that were ranked for the first time. Frankfurt School of Finance and Management in 41st place is the year’s highest new entrant. The German school has one of the most gender-balanced programmes, with women accounting for 49 per cent of students.
《为奴十二载》(12 Years A Slave):这是一部奇特的文娱片,令人震动、悲伤。本片导演史蒂夫?麦昆(Steve McQueen)大胆拍摄了一个关于美国奴隶制时代的故事,发人深省,是一部迎合主流观众口味的佳作。这部影片证明了艺术的力量,同时说明影迷们在他们选择观看的电影中渴求影片的本质和意义,这一点也令人振奋。该片编剧为约翰?里德利(John Ridley),主演包括切瓦特?埃加福特(Chiwetel Ejiofor)、露皮塔?尼永奥(Lupita Nyong'o)、迈克尔?法斯宾德(Michael Fassbender)等人。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

“It is exceptionally unlikely that we would be witnessing a record year of warmth, during a record-warm decade, during a several decades-long period of warmth that appears to be unrivaled for more than a thousand years, were it not for the rising levels of planet-warming gases produced by the burning of fossil fuels,” Michael E. Mann, a climate scientist at the Pennsylvania State University, said in an email.
They say that it is especially risky to use the same password for entertainment sites as for email and social networking accounts.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

1. Apple. Brand love: 57% / Rank: 32

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

For the first time in six years, a new challenger has topped the FT’s ranking of executive MBA programmes.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

这里并不是要给特斯拉浇一瓢冷水。它已经证明自己具有生产一款复杂、先进且外观诱人的产品的能力。但无论是特斯拉自己的内部预测,还是投资人对其股票的追捧,都基于同样一个预期,那就是特斯拉未来依然会延续最近的大热势头。这是一种危险的假设,原因如下:
Businesses are already responding: Job openings in November hit the second highest level in 14 years. In another telltale sign, people are quitting jobs at the fastest rate in five years. Research shows that people who quit one job for another typically do so because they are offered higher pay.
安吉利拉瓦尔(Anjli Raval)
单词ballroom 联想记忆:

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

科技巨头腾讯创始人马化腾凭借2790亿元的身家位居榜首,阿里巴巴的马云和恒大集团的许家印紧随其后,其个人财富分别为2600亿元和2290亿元。
The worst of 2015
本田公司希望NSX将再度彰显其技术致胜的美誉,也希望NSX能提升本田作为高端汽车和卡车制造商的品牌形象。去年美国汽车市场销售增长5.9%,但本田在美销量仅微增1%——这意味着该公司失去了一部分市场份额,最重要的是,本田在与其两大主要对手丰田和日产的角逐中落于下风。
如果计划生育法修正草案在星期日被中国最高立法机关批准,全面二孩政策的实施将不再会有任何法律障碍。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

单词senior 联想记忆:
We’ve all had them: bosses and managers who make our work lives terrible and couldn’t manage a stack of paper clips, let alone a team of employees. I’ve written about the traits that make for bad bosses before, and in that article, a thoughtful commenter came up with his own list of what makes a good boss。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

de下,put放-下放权力-代理
It’s ironic that in a country as populous as China, a meme about loneliness would be so popular. This seemingly irrational line has been repeated in every possible permutation, on every possible occasion, e.g. “What big brother is reading not a book, but loneliness.”
安德森想让男人们脸上的毛发丰富多样,每个演员脸上装饰的胡子都不太一样。它是名符其实的时髦派风格,从一字胡、八字胡,再到杰夫·戈德布拉姆(Jeff Goldblum)的黑灰色山羊胡。
雪莉·巴赛为007系列电影演唱了两首名曲,这是其中之一。从某种程度上来说,007系列电影一直讲述的是心愿达成的故事。观众在享受剧情的同时,耳旁听着最棒的歌手用强有力的声音唱着关于贪欲的歌词,真是恰到好处。所以无论你对这部电影抱有何种看法(尽管这不是007系列最佳电影之一),巴赛拥有上好的素材,创作了让人眼前一亮的歌曲。
The Producer Price Index (PPI), which gauges factory-gate prices and is a major indicator of economic briskness, rose by 6.3% in 2017, compared with a minus 1.4% for 2016, reversing the trend of continual decline since 2012.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

最佳歌曲:
The UK’s Warwick Business School recorded the best progression at the top, moving up from 16th to ninth place, while the Shanghai Advanced Institute of Finance (Saif), based at JiaoTong University, enjoys the bestprogression overall, jumping from 28th to 14th place.
但是亚利桑那州的经济前景现在已经大为好转,随着住房市场的稳定,失业率在5月份降至7.8%,创下经济衰退后的新低。为了评选今年的美国最适宜经商的州,我们评估了35项指标以判断哪些州的经商条件最佳,哪些最差,这些指标中就包括就业预期。根据穆迪分析公司(Moody’s Analytics)的统计,在今后五年中,亚利桑那州的就业增长速度预计将达到每年3%。到2017年,亚利桑那州增长的就业岗位预计每年将把家庭收入提高3.6%,在全美各州中位居第二,仅次于伊利诺伊州。亚利桑那州的就业增长和经济增长保持同步,穆迪预计该州的经济增长速度为每年4.6%,达到美国的最佳水平。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

The number of students who will study abroad after graduation has also seen a drop, down from 4.8 percent last year to 3.4 percent.
这是中国首次占据榜单前三甲以及在前10强中占了5名。中国工商银行连续两年占据第1名的宝座,中国建设银行次之,而且中国农业银行向上移动了5名成为第3名。这三大银行与排在第9名的中国银行一起跻身前10强,中国银行是“四大国有银行”中的另一个成员。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The United Kingdom ranks No. 3 overall. It ranks No. 4 in Power and No. 5 in Cultural Influence.
自该学校的国际管理学硕士(International Master in Management)项目首次被纳入榜单以来,该学校的排名在过去两年上升31个位置。
Much joy to you in the up coming year. May the warmest wishes, happy thoughts and friendly greetings come at New Year and stay with you all the year through.让温馨的祝愿、幸福的思念和友好的祝福,在新年来到你身边,伴你左右。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

报告称,北上广深等一线城市居民承受着较大的经济压力;而四线及以下城市的工作机会较少,人脉在生活的各个方面都起着重要作用。
《傲骨贤妻》(The Good Wife):艾丽西娅(Alicia)的秘密暧昧对象威尔(Will,乔希·查尔斯[Josh Charles]饰)在第五季末死去,CBS频道的这部性感法庭剧似乎要完蛋了,但是第六季却似乎充满了疯狂的能量——艾丽西娅初露头角的政治竞选、新旧公司的权力之争、合伙人卡里(Cary)的棘手法律事务。艾丽西娅不再那么完美,《傲骨贤妻》因此更好看了。
That pushed the state share of total investment for the year to date down marginally to 36.6 per cent, still the largest share since 2011 and reflecting the outsize role of government spending in sustaining economic growth during 2016.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 上游利好刺激家居行业谋突破
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

你可以点击此处浏览全部的假新闻,这里列出的是排名前五的假新闻:

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

n. 规章制度,草案,协议,外交礼仪

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

3.解决问题的好手
A member of staff at the Yizheng Museum told MailOnline that the bronze item had been found inside the tomb of an aristocrat in the West Han Dynasty (206 BC–8 AD) the first part of the Han Dynasty.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

3. Jia Junpeng, your mom wants you to go home for dinner.”
But whether another hit product can emerge to fend off questions about Apple’s life after Jobs, Mr Cook learnt long ago to be patient and trust his instincts, just as he did when he ignored the doubters to join the then-struggling company in 1998.
认为西方民主政体不会受影响将是愚蠢的。
全球其他地区能加以配合吗?

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

排放量去年的增幅比过去十年中2.5%的平均增长率略低,而且排放量增幅之所以下降,很大程度上是由中国经济增长放缓所引起的。中国是世界上最大的温室气体排放国。可能还需要再花一到两年时间,才能弄清楚中国排放量的增长究竟有没有放缓,还是最近数年那种极高的增速仍会持续。
stressful

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

你花在上网上的时间多于你工作的时间
v. 投,掷,抛,铸造,丢弃,指定演员,加起来,投射(目

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 红木家具回购市场尚不成熟
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

荷兰合作银行表示,预计大豆价格将保持强劲,目前在1蒲式耳10美元上方,同时由于需求稳定上升,预计奶制品价格明年也将上涨。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

几十年来,史泰龙塑造的这个弱者形象一直在鼓舞人们为目标奋斗,他们中既有运动员又有非运动员。洛奇是当地一名贫穷的拳击手,因与世界重量级冠军阿波罗·祈利比试而崭露头角。由于祈利的严格训练和相对无情,洛奇成了第一个与他打上15回合的挑战者。
诺贝尔化学奖颁给了一位尝试制作世界上最小的分子机器的科学家。
北京正努力在年底前完成《区域全面经济伙伴关系协定》(Regional Comprehensive Economic Partnership,简称RCEP)。该协议长期以来被称为中国面对《跨太平洋伙伴关系协定》(Trans-Pacific Partnership agreement,简称TPP)的对策,以及代表了中国争取区域贸易霸权的努力。
采光。在工作中,光线是很重要的,不要用上大学时候的那个小台灯了,用个更别致更有创意的灯吧。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

2011年在达洛伊西奥15岁时,他就曾获得来自李嘉诚的种子投资。一年之后Summy发布,并在短短一个月内吸引了500,000名用户,在28个国家登上了新款应用软件热度榜的首位。对于一个连高中都还没毕业的人来说,雅虎的收购可谓意义深远。不过,达洛伊西奥的过人之处可不只是技术知识丰富这一点。在他连胡子都不用刮的时候,他就强烈向往、渴望著有朝一日能在科技领域做出一番大的成就。不仅要创新,还要有所成就,当然,还要大把赚钱。
Students were then asked to move the dispenser to the teachers' office where teachers then called the police.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Although the average punctuality rate of the surveyed airports rose 7% year-on-year to 70.4% in 2016, the average delay time was 33 minutes.
Armistice Day became an official U.S. holiday in 1938, and remained so until 1954, when it was renamed Veterans Day in the aftermath of both World War Two and the Korean War. It is separate from Memorial Day, which is observed on the last Monday in May and honors servicemen and women killed in war.
We will make solid efforts to pursue the Belt and Road Initiative.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Set in 1950's London, Reynolds Woodcock is a renowned dressmaker whose fastidious life is disrupted by a young, strong-willed woman, Alma, who becomes his muse and lover.
The Belty is great that it uses technology to track fitness, water intake, and posture, but for $395, you might be better off getting the same in a stylish smart watch or activity tracker.
过去4年里束缚经济增长的主要因素就是停滞不前的薪酬水平。时薪年平均增长率仅为2%—仅有过去美国长期薪酬增长率的三分之二。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

她说,在人民币升值的同时,与中国在旅游业方面构成竞争关系的国家(如日本)的货币贬值,这意味着到其他一些亚洲国家旅游的费用更加便宜,而来中国旅游更贵了。
The Shape of Water

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 家居产品深陷环保质量漩涡
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 3月租房旺季 需求强劲租金企稳
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

人类想知道“这是为什么?”
Meanwhile, there are other factors holding back the Asian ETF market that some sceptics fear will hold back development of the retail side.
每天向大家推送短小精悍的英语学习资料.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

如果你在寻找一个免费的客户关系管理系统,Zoho或许正适合你。为什么呢?因为它提供了集成的可能性。比如只需添加你的API密钥,就可以轻松与JotForm和Unbounce集成。这意味着只需要几秒钟的时间,销售线索就可以自动发送到你的CRM系统。对于一款免费软件来说,这已经非常强大了。
万分沮丧之下,他发明了可以允许自拍的东西:他称之为"伸缩杆"。因为智能手机还没发明出来,所以,连接在自拍杆末端的是一个微型相机。在杆的前端有一面小镜子,方便使用者调整他们在相机里的姿态。他在1983年为"伸缩杆"申请了专利。虽然自拍杆进行了大量生产出售,却属商业败笔——相片的质量比较差。另外,以前的研究表明,那时的女士会因自己有自拍的想法而感到尴尬。在2000年,自拍杆被韦恩·弗洛姆(Wayne Fromm)重新发明,那时,上田宏的"伸缩杆"专利期尚有三年。弗洛姆称他的自拍杆为"快捷豆荚"。他认为他才是当今自拍杆的发明者,甚至起诉其他自拍杆生产者。当被问到上田宏的自拍杆时,弗洛姆评论说它们是"先前的艺术"。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 3D打印建材 40分钟造间房
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

但是,我们也许终于走到了终点。也许只有在该剧落幕之后,它对成衣秀的影响力才会终结。也许我们对历史无休止的模仿(是的,我们曾模仿70年代的风格以及80年代的大波浪头和高垫肩)才会最终停止。
在佛罗里达州博卡拉顿林恩大学的辩论,在外交政策和安全上奥巴马有一个固有的优势。作为总统,能接触到情报分析员、外交官和将军的每日简报,他能更好的概括,好像在上半场的辩论中他支配着罗姆尼。
the Dutch lender that is a leading financier to farmers and agribusinesses around the world.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

我们的外汇储备是充裕的,是足以支付进口和满足短期偿债需要的。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 科勒在海口开设大型展厅
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

The 54-year-old has already said he wants Bain to be recognised as a go-to provider of digital expertise. The question is whether this will be achieved through acquisitions, poaching teams or retraining the existing workforce.
但是,小牛队的确应该摆烂。同样的还有国王队,还有热火队,还有魔术队。这些都是中游的球队,即使在最乐观的预测中都没有很高的排名。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

The Death Proof star's early success was on the independent film circuit. But then she met Harvey Weinstein in a hotel room and it is there that she alleges he raped her.
这栋房屋坐落在街道上的一处小山丘上。房屋的入口处是一个大玻璃门廊,有砖砌的地面和对着湖的玻璃窗墙。翻修工程保留了花格镶板的天花板和原建筑部分大量运用的木材。其布局规划是开敞式设计,几乎每个房间都可以从观景窗看见湖景。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

美国和欧洲钢铁行业指责中国受到高额补贴的钢铁部门向全球市场大量输出钢铁,以低于生产成本的价格“倾销”,拉低了国际价格。近年来钢铁价格暴跌已经造成从澳大利亚到英国、乃至美国部分工业中心的全球范围的工厂大量倒闭。
Identity, as academics define it, falls into two broad categories: “achieved” identity derived from personal effort, and “ascribed” identity based on innate characteristics.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

中国社会科学院近日发布的《中国社会心态研究报告(2016)》显示,一线城市居民生活压力较大,不过小城市也未必是宜居地。
“The impact of lower prices on the slide in profits is worsening,” he said.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Mila Kunis placed second on the list, followed by Kate Upton, pop star Rihanna and Emma Stone.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

康乃尔大学商学院院长兼该报告的合著者苏米特拉·达塔表示:“在提高创新素质上面投资是 缩小创新鸿沟的关键。”
inspection
Last year, only 930,000 of the 1.39 million qualified finally entered the exam halls.
美国

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

BACKSTROM (Fox, Jan. 22) Last year, Fox tried a show about a self-destructive lawyer (“Rake,” starring Greg Kinnear) that was based on an Australian TV series. That didn’t work, but now the network is trying a show about a self-destructive detective (played by Rainn Wilson of “The Office”) that’s based on a series of Swedish novels. The show was created by Hart Hanson, who was responsible for the Fox series “Bones,” but in the pilot Mr. Wilson’s Backstrom looks a lot more House-like than Bones-like.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

A person walks through snow Tuesday in Belington, West Virginia. Superstorm Sandy buried parts of West Virginia under more than a foot of snow on Tuesday.
Fuel for this latest burst of Tesla mania came from none other than Chairman and CEO Elon Musk in comments he made during an analyst call on July 31. The big news wasn’t that Tesla reported higher production for the second quarter and beat earnings estimates again.
对于购房者,也不都是坏消息:房价明年(2015年——译注)仍将上涨,但步伐可能会从飙涨趋于平缓。“房价不会一味地陡然上涨,”柯克兰集团(Corcoran)的首席执行官帕梅拉·利伯曼(Pamela Liebman)说,“买家都有点疲劳了。”

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

“有个家伙请了一支军乐队来陪他宣布离职。”
“I saw a woman die and I saw the president of the United States refuse to unequivocally condemn the people who killed her.”

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Warm greetings and best wishes for happiness and good luck in the coming year.衷心祝福来年快乐、幸运!
《那年花开月正圆》并非改编自小说,而是基于真实人物女商人周莹的故事拍摄的。周莹生在清朝(1644-1911),是当时的陕西省女首富。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 家居行业求变 谨慎选购为上策
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

But only 14,000 tourists took advantage of the visa-free stopover, according to the Beijing General Station of Exit and Entry Frontier Inspection, well short of the 20,000 target officials had previously predicted.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 8月佛山陶瓷价格指数走势分析
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Tesla has an order backlog of $226 million. At the production run rate of 1000 cars a week expected at the end of 2014, that translates to a 30-week backlog.
欧盟的美洲布局
不是因为我乐意看到一部精彩的电视剧剧终——如今已被公认为电视剧的黄金时代,而它正是这个时代的先驱。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Chinese imports fell 18.8 per cent in October from the same month a year earlier, a slight improvement from the 20.4 per cent year-on-year fall in September. Sharply lower prices of oil and other commodities also helped scythe the bill.
That will require different skills — notably a clearer vision among leaders of their organisation’s shared purpose. The dilemma of how to lead “teams” of robots and humans will become even more pressing this year.
他表示,目前腾讯旗下的游戏和直播应用不需要实名注册,不过腾讯公司正在考虑建立一个平台,以方便家长监护孩子的行为。
Here are five things consumers and investors can count on (probably) in 2015:

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

蒂莫西·哈顿(Timothy Hutton)的小金人对归属问题做出了最好的答复,哈顿曾在影片《凡夫俗子》中表现十分优异,并成为奥斯卡金像奖最年轻的最佳配角奖得主。在数年前的一次聚会中,他的姐姐突然从冰箱里拿出小金人,和啤酒一起随机放在某处,使宾客们能够碰巧在路上拿到它,从而提提神。显然,现在它还在那里。
为回应这起事件,借贷宝12月1日在其新浪微博上发表了一份公告,强调用裸照作抵押贷款是用户之间的私人交易,该公司无法加以管理。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

For example, taxi drivers who take a detour or refuse passengers can also be fined a maximum of 2,000 yuan.
Warriors winning title was inevitable
As the cameras cut away to the cast and crew of "La La Land" hugging, Beatty could be heard saying something such as, "It says Emma Stone," with Dunaway replying, "What?" As the La La Land cast were walking on stage to accept the accolade, a stagehand standing in the wings could be heard saying "Oh ... Oh my god, he got the wrong envelope".

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 中国城镇家庭负债率升至5.5%
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在中国版推特新浪微博上,很多网民为男孩危急情况下的勇敢、淡定点赞。
In fact, one ancient saying was, "ifyou have Kucha, only one percent of the states in the Western Frontiers remain unsubmissive."

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